Novartis Held Accountable For Concealing Tasigna Atherosclerosis Risk
The deceptive practices of Novartis AG have not escaped government regulators in the United States
Tuesday, May 15, 2018 - Anti-cancer chemotherapy drug Tasigna was originally approved by the FDA in 2007 for use in the treatment of Philadelphia chromosome-positive (Ph+) positive myeloid leukemia (CML). Tasigna is the trade name given to nilotinib, manufactured by Novartis AG. The drug is made from hydrochloride monohydrate salt a small-molecule tyrosine kinase inhibitor. A tyrosine kinase inhibitor blocks the enzymes that activate certain proteins that are necessary and common to cancer cells. By blocking the addition of a phosphate to the protein, cell reproduction in disrupted. Tasigna has shown to be extremely effective in treating CML however the drug carries a unique and life-threatening side effect.
Tasigna Causes Atherosclerosis
Tasigna patients are reporting that they have developed full-blown atherosclerosis and have experienced necrosis of the lower extremities, paralysis from strokes, and sudden death from heart attack. Many patients question whether the risks of Tasigna are worth the benefits and cancer patients need to know their alternatives. Tasigna atherosclerosis victims are hiring a Tasigna atherosclerosis lawyer and filing a personal injury or a wrongful death claim against Novartis alleging the company knew of the atherosclerosis risks, reported them to Canadian health officials, but did nothing to warn the medical community or cancer patients taking Tasigna in the United States.
On April 12, 2013, Health Canada reported "important safety information regarding reports of atherosclerosis-related conditions in patients treated with TASIGNA* (nilotinib)," that was disclosed to them by Novartis Pharmaceuticals Canada. The report "Cases of atherosclerosis-related conditions have been reported during clinical trials and post-marketing experience with the use of TASIGNA*." Canadian cancer physicians were immediately notified of the findings and were told to pre-screen patients for signs of heart disease of blood abnormalities by having them undergo blood tests and an electrocardiogram prior to initiating Tasigna treatments and to avoid Tasigna if a patient showed signs of heart disease. Physicians were urged to test existing and post Tasigna treatment patients for signs of heart disease as well. Between 2005 and 2013 a total of 277 cases of Tasigna atherosclerosis were reported.
The Novartis/Health Canada report describes Tasigna as causing "peripheral arterial occlusive disease (hardening and narrowing of the arteries that supply blood to the arms and legs), femoral artery stenosis (hardening and narrowing of the arteries located in the upper thigh), coronary artery stenosis (narrowing or hardening of the arteries supplying the heart that causes angina (chest pain), carotid artery stenosis (narrowing or hardening of the carotid artery in the neck), and cerebrovascular accident (stroke)." Source: http://healthycanadians.gc.ca/recall-alert-rappel-avis/hc-sc/2013/26659a-eng.php
It is not difficult to understand the motivation behind Swiss pharmaceutical giant Novartis' failure to explicitly warn the US medical community of the life-threating side effects of Tasigna. Global sales of Tasigna topped $1.6 billion in 2016, the largest percentage of which coming from the lucrative US market. Novartis profited from US Tasigna sales for years until their deception caught the attention of the U.S. Department of Justice. The agency sued Novartis and levied a fine of $1 billion dollars against Novartis, settling for a payment of $390 million. Novartis admitted to paying illegal kickbacks to specialty pharmacies to recommend Tasigna over competing brands, misbranding the drug, falsely advertising, and willfully concealing their knowledge of the Tasigna atherosclerosis risk since 2011 from American doctors and cancer patients.
More Recent Tasigna Atherosclerosis Lawsuit News:
- Tasigna Patients Are Warned of The Risk of Sudden Death | 5/13/2019
- Tasigna's Atherosclerosis Risk Is Well-Documented By Researchers For Peer-Reviewed Medical Publications | 5/8/2019
- Tasigna's Atherosclerosis Side Effect Is Not Forgotten | 4/17/2019
- Trying Tasigna As A Last Resort May Make Sense To Terminally Ill Cancer Patients | 4/12/2019
- Novartis Claim Tasigna Can Help Parkinson's Patients is Met With Skepticism | 4/4/2019
- Novartis Failed To Warn American Doctors Who In Turn Failed To Warn Patients of Tasigna's Atherosclerosis Risks | 3/20/2019
- Tasigna Is Being Repurposed To Treat Parkinson's Disease | 3/14/2019
- Some Patient Can Cease Taking Tasigna But They May Have Already Developed Atherosclerosis | 3/12/2019
- Health Experts Warn of Potentially Deadly Tasigna Drug Interactions | 3/5/2019
- The Potential To Someday Stop Tasigna Treatments Should Not Be An Incentive To Take The Drug | 2/28/2019
- Tasigna Studies Show The Drug Should Be Taken As A Last Resort | 2/24/2019
- Cancer Doctors and Medical Websites Should Take Tasigna's Atherosclerosis Risks More Seriously | 2/18/2019
- The FDA May Be Putting Children's Lives In Danger By Ignoring Tasigna's Atherosclerosis Risk | 2/12/2019
- The FDA May Have Overlooked Tasigna's Atherosclerosis Side Effect When Approving its Usage by Children | 2/5/2019
- Children With Cancer May Now Start Taking Tasigna | 1/31/2019
- Studies Reported by Leading Experts Focus on Tasigna Toxicity | 1/25/2019
- Novartis Has a History of Deceptive Sale Practices That Taints Their Credibility | 1/22/2019
- Novartis Changes Tasigna's Label But Not Its Toxicity | 1/16/2019
- Tasigna Doctors May Be Ignoring Atherosclerosis Risks | 1/11/2019
- Cancer Doctors Prescribing Tasigna Should Be Trained Like Heart Specialists | 1/8/2019
- Tasigna is Effective in Treating Chronic Myeloid Leukemia | 1/1/2019
- Early Warning Signs of Chronic Myeloid Leukemia (CML) | 12/5/2018
- CML Patients in Remission May Discontinue Taking Tasigna | 12/1/2018
- Tasigna's Atherosclerosis Warnings is Rarely Seen by Cancer Patients | 11/28/2018
- Novartis' Failure to Warn the FDA May Have Led to Atherosclerosis in As Many As One in Four Tasigna Patients | 11/12/2018
- Novartis Highlights Tasigna's Effectiveness yet Downplays The Drug's Deadly Side Effects | 11/8/2018
- Novartis Takes Advantage of Tasigna's Catch 22 | 10/30/2018
- Tasigna Atherosclerosis Ignored by Novartis Celebrity Spokesperson | 10/24/2018
- Oncologists May Be Ignoring the Cardiovascular Side Effects of Tasigna | 10/16/2018
- The FDA Atherosclerosis Warning Came Too Late for Tasigna Patients in the United States | 10/8/2018
- One-Third of Tasigna Patients Could Face Coronary Bypass Surgery | 10/4/2018
- Billion Dollar Fines Are Just a Cost of Doing Business For Novartis | 10/2/2018
- Cancer Patients Should View Novartis' New Tasigna Label With Scepticism | 9/28/2018
- Novartis Boasts of Tasigna's Effectiveness While Ignoring the Atherosclerosis Side Effects | 9/27/2018
- Tasigna May Be One Of The Most Deadly Drugs On The Market Today | 9/25/2018
- NBA Star's Arterial Blockage May Have Been Caused by Taking Tasigna | 9/22/2018
- Taxpayers Saved Billions By Novartis AG Whistleblower | 9/20/2018
- Tasigna Carries The Unacceptable Risk of Developing Atherosclerosis and Amputation | 9/19/2018
- Tasigna's Cancer-Fighting Success May Be Tempered By The Risk Of Sudden Death | 9/17/2018
- Novartis Pulled No Punches In Warning Canadians About The Atherosclerosis Related Side effects Of Tasigna Yet Said Nothing To Warn Cancer Patients In The United States. | 9/11/2018
- Novartis is a Repeat Offender for Fraudulent Drug Marketing | 8/29/2018
- Peripheral Artery Disease Plagues Tasigna Patients | 8/27/2018
- Patients Could Have Benefited From Gleevec's Generic Alternative | 8/21/2018
- Novartis/Tasigna Lawsuit May Seek Punitive Damages | 8/17/2018
- Tasigna Atherosclerosis Trial Set to Proceed | 8/14/2018
- Medical Websites Ignore Tasigna's Risks | 8/10/2018
- Novartis haste in rushing Tasigna to market has cost patients their lives | 8/8/2018
- Tasigna's Side Effects Require Special Attention From Prospective Patients | 8/6/2018
- Novartis Whistleblower Receives $12 Million For His Efforts | 7/31/2018
- Tasigna Atherosclerosis Hidden From Americans | 7/30/2018
- Gleevec Was a Cancer-Curing Miracle Drug | 7/26/2018
- Tasigna Stroke Victim's Trial to Proceed in Florida | 7/24/2018
- Novartis Employee Blows Whistle on Tasigna Fraud and Others | 7/20/2018
- Tasigna Side Effects Are Worse Than Cancer | 7/18/2018
- Tasigna Cancer Medication Carries More Risks Than Others | 7/11/2018
- Specialty Pharmacists Bribed to Prescribe Tasigna | 7/6/2018
- Novartis Billion-Dollar Fine for Fraudulent Marketing Tactics | 7/2/2018
- Tasigna Black Box Warning Addendum | 6/29/2018
- Tasigna Replaced Gleevec and Patients Suffered | 6/25/2018
- Specialty Pharmacists Selling Tasigna Compromised Ethical Standards | 6/20/2018
- US Department of Justice Fines Novartis One Billion Dollars | 6/13/2018
- Tasigna Sudden Death Warning | 6/11/2018
- Tasigna Cancer Treatment Poses Scary Risks | 6/7/2018
- Novartis Fraudulent Marketing Deception | 5/29/2018
- Tasigna Atherosclerosis Warning Never Made it to the US | 5/25/2018
- Novartis Tasigna Anti-Cancer Drug Has Side Effects That Include Sudden Death | 5/22/2018
- Tasigna Replaced Gleevec Under Fraudulent Circumstance | 5/18/2018
- Tasigna Chemotherapy Carries a Sudden Death Warning | 5/10/2018
- Novartis Warns That Tasigna Can Cause Atherosclerosis | 5/6/2018
- Tasigna Poses Atherosclerosis Amputations Risk | 5/3/2018
- Tasigna Rushed to Market to Replace Gleevec | 12/29/2017
- Whistleblower Saves American Taxpayers Millions | 12/22/2017
- Gleevec-the Novartis AG Wonder Drug | 12/20/2017
- Tasigna Warnings | 12/18/2017
- Tasignas Black Box Warning Links The Drug To Atherosclerosis | 12/15/2017
- Novartis Fails To Warn The U.S. Medical Community About The Side Effects of Tasigna | 12/11/2017
- Tasigna Replaces Gleevec as the Novartis AGs Signature Anti-Cancer Chemotherapy Drug | 12/6/2017
- The Unmistakable Signs of Peripheral Artery Disease | 12/1/2017
- Whistleblower Causes Public Alert to Tasigna Side Effects | 11/27/2017
- The Estate of a California Man is Suing Novartis | 11/20/2017
- Ex-Novartis Salesmanager Blows The Whistle On Illegal Drug Marketing | 11/13/2017
- U.S. Cancer Patients Receive Tasigna Atherosclerosis Warning | 11/6/2017
- Novartis Marketed Tasigna to Replace Gleevec | 11/3/2017
- Leukemia Patients May Suffer From Heart Disease as Well | 10/30/2017
- Novartis' Potentially Misleading Drug Marketing Campaign | 10/23/2017
- Health Canada Issued a Tasigna Health Warning In 2013 | 10/16/2017
- Lawsuits Allege Novartis Was Aware of The Side Effects of Tasigna Yet Failed to Warn The American Public | 10/9/2017
- Tasigna Chemotherapy Atherosclerosis-related Side Effects | 10/2/2017
- The Onder Law Firm Seeks to Hold Novartis Accountable for the Suffering Tasigna Has Caused Families | 9/29/2017
- Novartis Fails to Warn About Tasigna Atherosclerosis | 9/22/2017
- Side Effects of Tasigna Cancer Drug Include Atherosclerosis and Peripheral Artery Disease | 9/15/2017
- Novartis Put Profits Ahead of Patients | 9/7/2017
- Novartis Failed to Warn the American Medical Community of the Side Effects of Tasigna | 9/1/2017
- Atherosclerosis Linked to Tasigna Anti Cancer Drug | 8/18/2017
- You Can Sue Novartis If You Have Developed Atherosclerosis-Related Conditions After Taking Tasigna | 8/11/2017
- Who Can Be Considered A Tasigna Victim | 8/4/2017
- Novartis AG makers of Tasigna Failed to Warn Public of the Dangerous Side Effects | 7/14/2017
- Tasigna Anti Cancer Drug Lawsuit | 7/7/2017
- Tasigna Drug Warning for Peripheral Arterial Disease | 6/30/2017
- Tasigna Cancer Treatment Drug Lawsuit | 6/26/2017
- Novartis International AG Lawsuits | 6/23/2017
- Lawsuits Against Novartis International AG Makers of Tasigna | 6/21/2017
- Tasigna Peripheral Artery Disease Warning | 6/19/2017
- Tasigna Lawsuits Against Drug Makers Novartis | 6/16/2017
- Atherosclerosis of the Aorta Linked to Tasigna Anti-Cancer Drug | 6/12/2017
- Makers of Tasigna Leukemia Drug Lawsuit | 6/9/2017
- Tasigna a Cancer Drug Treatment | 6/5/2017
- Tasigna Peripheral Arterial Disease | 6/1/2017
Lawyers for Tasigna Atherosclerosis Lawsuits
Attorneys handling Tasigna lawsuits for leukemia, non-Hodgkin lymphoma, and multiple myeloma offer free, no-obligation case review for individuals and families who believe they may have grounds to file a Tasigna lawsuit. Working on a contingency basis, these attorneys are committed to never charging legal fees unless they win compensation in your Tasigna lawsuit. The product liability litigators handling Roundup claims at the Onder Law Firm have a strong track record of success in representing families harmed by dangerous drugs and consumer products.