Health Experts Warn of Potentially Deadly Tasigna Drug Interactions
Leading health professionals have reported that certain drug interactions with Tasigna can be fatal
Tuesday, March 5, 2019 - Patients that are diagnosed with cancer are in for the fight of their lives and the last thing they would expect is that the anti-cancer drugs that their doctor prescribed could be even more deadly than the disease itself. That is the reality, however, for tens of thousands of cancer patients taking one of the world's most popular and heavily-promoted prescription drug. Anti-cancer chemotherapy drug Tasigna is one of the most effective in fighting those diagnosed with Philadelphia chromosome-positive chronic myeloid leukemia (Ph+ CML) in its chronic phase, but also one of the riskiest. Tasigna (nilotinib) cancer patients risk sudden death from a condition known as QT prolongation. According to the Mayo Clinic, QT Prolongation, also known as Long QT syndrome, "is a heart rhythm disorder that can cause serious irregular heart rhythms (arrhythmias). ... In long QT syndrome, your heart muscle takes longer than normal to recharge between beats. This electrical disturbance, which often can be seen on an electrocardiogram (ECG), is called a prolonged QT interval." Novartis AG, maker of Tasigna warns potential patients of the very real possibility of suddenly dropping dead after taking Tasigna. Doctors are warned not to give Tasigna to patients that are taking medications or have an implanted device to correct an irregular heartbeat. Novartis also warns that Tasigna may interact with other heart or blood thinning medications. Patients that develop lightheadedness, feel faint, or develop heart palpitations are urged to call their doctor immediately. Tasigna Atherosclerosis lawyers representing national Tasigna cases offer a free consultation and no obligation to file a claim.
Adverse drug interactions can trigger sudden death from QT prolongation syndrome. Medsafe.gov lists the following non-cardiac medication as "possibly associated with the increased risk of QT prolongation. , anti-infectives Azithromycin, Roxithromycin, Telithromycin, Moxifloxacin, and Amantadine, anti-emetics Ondansetron, Dolasetron, and Granisetron, Antipsychotics, Risperidone, Quetiapine, Sertindole, Ziprasidone, Lithium, and Clozapine, Antidepressants, Escitalopram, and Venlafaxine, and finally Anti-cancer drugs, Tamoxifen, Nilotinib, and Lapatinib. Those drugs that present the most serious risk are Clarithromycin, Erythromycin, Chloroquine, Pentamidine, Domperidone, Cisapride, Haloperidol, Chlorpromazine, Methadone, and Terfenadine."
Doctors prescribing Tasigna must first perform a test on the patient called an Electrocardiogram (ECG) in order to make sure the patient's heart is strong and also to provide a baseline in which to compare future (ECG)s. ECGs are to be performed every 7 days while the patient is taking Tasigna treatments. In order to avoid QT prolongation syndrome, patients must not eat for at least 2 hours before taking Tasigna as well as at least one hour after the treatment ends. Tasigna patient cannot eat grapefruit nor use any product that contains grapefruit extract.
In addition to and no less serious than sudden death from QT prolongation syndrome, other Tasigna patients have suffered the adverse side effect of atherosclerosis, a rapid narrowing of the major arteries leading to the extremities, heart, and brain. Tissue death (necrosis or gangrene) could result if the toes and feet do not receive enough nutrient and oxygen-rich blood and amputation could be required. Heart attack and stokes
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No-Cost, No-Obligation Tasigna Lawsuit Case Review If You or a Loved One Suffered from Tasigna Complications
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