Tasigna Atherosclerosis Lawsuit News

Novartis Pulled No Punches In Warning Canadians About The Atherosclerosis Related Side effects Of Tasigna Yet Said Nothing To Warn Cancer Patients In The United States.

Canadian health officials were provided an urgent warning to be aware that Tasigna can cause atherosclerosis while no such warning made its way to the US market

Tuesday, September 11, 2018 - In April 2013, Novartis Pharmaceuticals Canada sent a letter to Health Canada warning about the atherosclerosis side effects associated with Tasigna and at the same time updated the drug's warning label. Studies have shown that patients were given Tasigna develop atherosclerosis, a narrowing of the major arteries leading to the extremities such as the feet and toes, as well as leading to the brain and heart. In the study approximately one-third of Tasigna patients required angioplasty to attempt to unblock their arteries, 22% required a stent placed in the artery to keep it open, and 22% required amputation of the toes, feet or lower legs. No warnings have been made to the cancer community or government health officials in the United States.

In a public communication, Canadians were warned that taking Tasigna causes atherosclerosis-related conditions. The Canadian health advisory reads as follows: "Tasigna is a prescription medicine used to treat adult patients at different stages of a type of leukemia called Philadelphia chromosome-positive chronic myeloid leukemia (Ph+CML). Cases of atherosclerosis-related conditions have been reported during clinical trials and post-marketing experience with the use of Tasigna. Patients should tell their healthcare professional if they have or have had any conditions that could cause atherosclerosis-related conditions such as a heart problem, high blood pressure, high cholesterol, or high glucose before starting Tasigna treatment. During treatment with Tasigna, healthcare professionals will check for signs of atherosclerosis. Healthcare professional will also check cholesterol and blood sugar levels before starting treatment and periodically thereafter."

Even if cancer patients make it through the rigors of anti-cancer chemotherapy treatments and the disease goes into remission, Tasigna patients may be merely trading one deadly disease for another. An atherosclerosis-related disease is irreversible and often lead to death. Health Canada describes Tasigna's side effects as causing peripheral arterial occlusive disease (legs and feet), femoral artery stenosis (thigh), coronary artery stenosis (angina, chest pain heart attack), carotid artery stenosis (neck and head leading to strokes. The study goes on to say that there were 277 cases of such atherosclerosis-related conditions reported to the Novartis health database from the years 2005 to 2013.

Swiss pharmaceutical giant Novartis AG may have put profits ahead of patient safety by failing to warn cancer patients in the United States of the dangers of taking Tasigna. Case after case of atherosclerosis-related diseases are now being reported and many Tasigna atherosclerosis patients are consulting with Tasigna attorneys to determine if they qualify to file a claim against Novartis AG for monetary compensation. To this day, Tasigna continues to be promoted and sold to the US cancer community and is recommended more and more for treatment of CML. The complete Novartis Tasigna atherosclerosis statement can be viewed at https://www.novartis.ca/sites/www.novartis.ca/files/Tasigna_DHCPL_E_June%209%202011.pdf and is the source of this article.

After being flooded with atherosclerosis-related adverse event reports, the US Food and Drug Administrations demanded that Tasigna carry a "boxed warning" to warn of the risk of abnormal heart rhythm (QT prolongation) and sudden death as well as myelosuppression, blockages in the heart or arteries cardiac and arterial vascular occlusive events.

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