Tasigna Studies Show The Drug Should Be Taken As A Last Resort

Tasigna is being over-promoted as a breakthrough cancer drug, encouraging its overuse

Sunday, February 24, 2019 - Tasigna, the brand name for anti-cancer chemotherapy drug nilotinib, is prescribed by oncologists to kill and stop the spread of cancer cells. The drug is approved by the Food and Drug Administration (FDA) for all patients one year of age or older, suffering from Philadelphia positive chronic myeloid leukemia (Ph+CML). CML is a type of blood cancer and one of the fastest spreading and most difficult to treat diseases. CML treatment requires a patient to take the most toxic drugs that carry the most severe side effects and produce potentially long-term negative medical consequences. The life-threatening long-term side effects of anti-cancer drugs called nilotinib were starting to appear in the oncology community as early as 2013. Nature.com was one of the first online publication to warn the public that CML drugs called nilotinib (Tasigna) could cause atherosclerosis and put a cancer patient's life at risk. Tasigna lawyers representing national claims can help to consult families or individuals harmed by Tasigna atherosclerosis.

On October 29, 2007, Nilotinib drug Tasigna received US approval to treat cancer patients suffering from CML with resistance or intolerance to existing therapies. An article dating back to 2013 outlines the diseases that are associated with nilotinib (Tasigna) as atherosclerosis including "coronary artery disease (CAD), cerebral vascular disease (CVD) and peripheral artery occlusive disease (PAOD)." The review cites two paper that was published in the medical journal "Leukemia," which found the link between those taking nilotinib and atherosclerosis. The report focused on a study where scientists screened 129 CML patients to check for peripheral artery occlusive disease (PAOD) and found five cases of overt PAOD. In another part of the study, 27 patient with existing PAOD were studied and it was determined that "all but one of these patients were exposed to nilotinib (Tasigna) therapy." Authors of the nilotinib study were concerned with the long-term survivability of patients due to "accelerated atherosclerosis with nilotinib" as a first-line of treatment only. Doctors were advised to start with the less toxic imatinib and only switch to nilotinib as a last resort.

In addition to the Leukemia study, the FDA has recently approved the use of Tasigna for children as young as one-year-old. In so doing, the FDA ignored the warnings of Tasigna causing atherosclerosis in otherwise healthy adults with cancer. A 2008 article in Cure Today (Cancer Updates, Research, and Education) shows children surviving cancer have as high as a 10-fold chance of developing atherosclerosis.

To their credit, the FDA has required Novartis AG, maker of Tasigna, to include a more thorough warning to be placed in Tasigna's product literature to warn consumers of the heightened risk of patients developing heart disease. The warning stresses oncologists monitor their patients, before, during, and after Tasigna (nilotinib) treatments for signs that they are developing atherosclerosis, a narrowing of the arteries caused by a buildup of fatty blood platelets called plaque. Atherosclerosis causes rapid plaque buildup resulting in less nutrient and oxygen-rich blood making its way to the extremities of the feet and toes potentially causing tissue death in the extremities that requires amputation.

More Recent Tasigna Atherosclerosis Lawsuit News:

• Tasigna Patients Are Warned of The Risk of Sudden Death | 5/13/2019
• Tasigna's Atherosclerosis Risk Is Well-Documented By Researchers For Peer-Reviewed Medical Publications | 5/8/2019
• Tasigna's Atherosclerosis Side Effect Is Not Forgotten | 4/17/2019
• Trying Tasigna As A Last Resort May Make Sense To Terminally Ill Cancer Patients | 4/12/2019
• Novartis Claim Tasigna Can Help Parkinson's Patients is Met With Skepticism | 4/4/2019
• Novartis Failed To Warn American Doctors Who In Turn Failed To Warn Patients of Tasigna's Atherosclerosis Risks | 3/20/2019
• Tasigna Is Being Repurposed To Treat Parkinson's Disease | 3/14/2019
• Some Patient Can Cease Taking Tasigna But They May Have Already Developed Atherosclerosis | 3/12/2019
• Health Experts Warn of Potentially Deadly Tasigna Drug Interactions | 3/5/2019
• The Potential To Someday Stop Tasigna Treatments Should Not Be An Incentive To Take The Drug | 2/28/2019
• Cancer Doctors and Medical Websites Should Take Tasigna's Atherosclerosis Risks More Seriously | 2/18/2019
• The FDA May Be Putting Children's Lives In Danger By Ignoring Tasigna's Atherosclerosis Risk | 2/12/2019
• The FDA May Have Overlooked Tasigna's Atherosclerosis Side Effect When Approving its Usage by Children | 2/5/2019
• Children With Cancer May Now Start Taking Tasigna | 1/31/2019
• Studies Reported by Leading Experts Focus on Tasigna Toxicity | 1/25/2019
• Novartis Has a History of Deceptive Sale Practices That Taints Their Credibility | 1/22/2019
• Novartis Changes Tasigna's Label But Not Its Toxicity | 1/16/2019
• Tasigna Doctors May Be Ignoring Atherosclerosis Risks | 1/11/2019
• Cancer Doctors Prescribing Tasigna Should Be Trained Like Heart Specialists | 1/8/2019
• Tasigna is Effective in Treating Chronic Myeloid Leukemia | 1/1/2019
• Early Warning Signs of Chronic Myeloid Leukemia (CML) | 12/5/2018
• CML Patients in Remission May Discontinue Taking Tasigna | 12/1/2018
• Tasigna's Atherosclerosis Warnings is Rarely Seen by Cancer Patients | 11/28/2018
• Novartis' Failure to Warn the FDA May Have Led to Atherosclerosis in As Many As One in Four Tasigna Patients | 11/12/2018
• Novartis Highlights Tasigna's Effectiveness yet Downplays The Drug's Deadly Side Effects | 11/8/2018
• Novartis Takes Advantage of Tasigna's Catch 22 | 10/30/2018
• Tasigna Atherosclerosis Ignored by Novartis Celebrity Spokesperson | 10/24/2018
• Oncologists May Be Ignoring the Cardiovascular Side Effects of Tasigna | 10/16/2018
• The FDA Atherosclerosis Warning Came Too Late for Tasigna Patients in the United States | 10/8/2018
• One-Third of Tasigna Patients Could Face Coronary Bypass Surgery | 10/4/2018
• Billion Dollar Fines Are Just a Cost of Doing Business For Novartis | 10/2/2018
• Cancer Patients Should View Novartis' New Tasigna Label With Scepticism | 9/28/2018
• Novartis Boasts of Tasigna's Effectiveness While Ignoring the Atherosclerosis Side Effects | 9/27/2018
• Tasigna May Be One Of The Most Deadly Drugs On The Market Today | 9/25/2018
• NBA Star's Arterial Blockage May Have Been Caused by Taking Tasigna | 9/22/2018
• Taxpayers Saved Billions By Novartis AG Whistleblower | 9/20/2018
• Tasigna Carries The Unacceptable Risk of Developing Atherosclerosis and Amputation | 9/19/2018
• Tasigna's Cancer-Fighting Success May Be Tempered By The Risk Of Sudden Death | 9/17/2018
• Novartis Pulled No Punches In Warning Canadians About The Atherosclerosis Related Side effects Of Tasigna Yet Said Nothing To Warn Cancer Patients In The United States. | 9/11/2018
• Novartis is a Repeat Offender for Fraudulent Drug Marketing | 8/29/2018
• Peripheral Artery Disease Plagues Tasigna Patients | 8/27/2018
• Patients Could Have Benefited From Gleevec's Generic Alternative | 8/21/2018
• Novartis/Tasigna Lawsuit May Seek Punitive Damages | 8/17/2018
• Tasigna Atherosclerosis Trial Set to Proceed | 8/14/2018
• Medical Websites Ignore Tasigna's Risks | 8/10/2018
• Novartis haste in rushing Tasigna to market has cost patients their lives | 8/8/2018
• Tasigna's Side Effects Require Special Attention From Prospective Patients | 8/6/2018
• Novartis Whistleblower Receives $12 Million For His Efforts | 7/31/2018
• Tasigna Atherosclerosis Hidden From Americans | 7/30/2018
• Gleevec Was a Cancer-Curing Miracle Drug | 7/26/2018
• Tasigna Stroke Victim's Trial to Proceed in Florida | 7/24/2018
• Novartis Employee Blows Whistle on Tasigna Fraud and Others | 7/20/2018
• Tasigna Side Effects Are Worse Than Cancer | 7/18/2018
• Tasigna Cancer Medication Carries More Risks Than Others | 7/11/2018
• Specialty Pharmacists Bribed to Prescribe Tasigna | 7/6/2018
• Novartis Billion-Dollar Fine for Fraudulent Marketing Tactics | 7/2/2018
• Tasigna Black Box Warning Addendum | 6/29/2018
• Tasigna Replaced Gleevec and Patients Suffered | 6/25/2018
• Specialty Pharmacists Selling Tasigna Compromised Ethical Standards | 6/20/2018
• US Department of Justice Fines Novartis One Billion Dollars | 6/13/2018
• Tasigna Sudden Death Warning | 6/11/2018
• Tasigna Cancer Treatment Poses Scary Risks | 6/7/2018
• Novartis Fraudulent Marketing Deception | 5/29/2018
• Tasigna Atherosclerosis Warning Never Made it to the US | 5/25/2018
• Novartis Tasigna Anti-Cancer Drug Has Side Effects That Include Sudden Death | 5/22/2018
• Tasigna Replaced Gleevec Under Fraudulent Circumstance | 5/18/2018
• Novartis Held Accountable For Concealing Tasigna Atherosclerosis Risk | 5/15/2018
• Tasigna Chemotherapy Carries a Sudden Death Warning | 5/10/2018
• Novartis Warns That Tasigna Can Cause Atherosclerosis | 5/6/2018
• Tasigna Poses Atherosclerosis Amputations Risk | 5/3/2018
• Tasigna Rushed to Market to Replace Gleevec | 12/29/2017
• Whistleblower Saves American Taxpayers Millions | 12/22/2017
• Gleevec-the Novartis AG Wonder Drug | 12/20/2017
• Tasigna Warnings | 12/18/2017
• Tasignas Black Box Warning Links The Drug To Atherosclerosis | 12/15/2017
• Novartis Fails To Warn The U.S. Medical Community About The Side Effects of Tasigna | 12/11/2017
• Tasigna Replaces Gleevec as the Novartis AGs Signature Anti-Cancer Chemotherapy Drug | 12/6/2017
• The Unmistakable Signs of Peripheral Artery Disease | 12/1/2017
• Whistleblower Causes Public Alert to Tasigna Side Effects | 11/27/2017
• The Estate of a California Man is Suing Novartis | 11/20/2017
• Ex-Novartis Salesmanager Blows The Whistle On Illegal Drug Marketing | 11/13/2017
• U.S. Cancer Patients Receive Tasigna Atherosclerosis Warning | 11/6/2017
• Novartis Marketed Tasigna to Replace Gleevec | 11/3/2017
• Leukemia Patients May Suffer From Heart Disease as Well | 10/30/2017
• Novartis' Potentially Misleading Drug Marketing Campaign | 10/23/2017
• Health Canada Issued a Tasigna Health Warning In 2013 | 10/16/2017
• Lawsuits Allege Novartis Was Aware of The Side Effects of Tasigna Yet Failed to Warn The American Public | 10/9/2017
• Tasigna Chemotherapy Atherosclerosis-related Side Effects | 10/2/2017
• The Onder Law Firm Seeks to Hold Novartis Accountable for the Suffering Tasigna Has Caused Families | 9/29/2017
• Novartis Fails to Warn About Tasigna Atherosclerosis | 9/22/2017
• Side Effects of Tasigna Cancer Drug Include Atherosclerosis and Peripheral Artery Disease | 9/15/2017
• Novartis Put Profits Ahead of Patients | 9/7/2017
• Novartis Failed to Warn the American Medical Community of the Side Effects of Tasigna | 9/1/2017
• Atherosclerosis Linked to Tasigna Anti Cancer Drug | 8/18/2017
• You Can Sue Novartis If You Have Developed Atherosclerosis-Related Conditions After Taking Tasigna | 8/11/2017
• Who Can Be Considered A Tasigna Victim | 8/4/2017
• Novartis AG makers of Tasigna Failed to Warn Public of the Dangerous Side Effects | 7/14/2017
• Tasigna Anti Cancer Drug Lawsuit | 7/7/2017
• Tasigna Drug Warning for Peripheral Arterial Disease | 6/30/2017
• Tasigna Cancer Treatment Drug Lawsuit | 6/26/2017
• Novartis International AG Lawsuits | 6/23/2017
• Lawsuits Against Novartis International AG Makers of Tasigna | 6/21/2017
• Tasigna Peripheral Artery Disease Warning | 6/19/2017
• Tasigna Lawsuits Against Drug Makers Novartis | 6/16/2017
• Atherosclerosis of the Aorta Linked to Tasigna Anti-Cancer Drug | 6/12/2017
• Makers of Tasigna Leukemia Drug Lawsuit | 6/9/2017
• Tasigna a Cancer Drug Treatment | 6/5/2017
• Tasigna Peripheral Arterial Disease | 6/1/2017

No-Cost, No-Obligation Tasigna Lawsuit Case Review If You or a Loved One Suffered from Tasigna Complications

OnderLaw, LLC is a St. Louis personal injury law firm handling serious injury and death claims across the country. Its mission is the pursuit of justice, no matter how complex the case or strenuous the effort. The Onder Law Firm has represented clients throughout the United States in pharmaceutical and medical device litigation such as Pradaxa, Lexapro and Yasmin/Yaz, where the firm's attorneys held significant leadership roles in the litigation, as well as Actos, DePuy, Risperdal and others. The Onder Law Firm has won more than $300 million in four talcum powder ovarian cancer lawsuits in St. Louis. Law firms throughout the nation often seek its experience and expertise on complex litigation.